Synthetic Adsorbents for Chromatographic and Smaller Scale (SS) Purifications

It’s well known that smaller size resins are required to obtain higher purity and better recovery in chromatographic separation of pharmaceuticals.

Sorbtech offers several types of Mitsubishi synthetic adsorbent grades in very useful particle size distribution for industrial-scale chromatography.

Aromatic Type – Diaion® HP20SS and SP20SS

These adsorbents are directly polymerized, small particle size version of HP20. The wide pore polymer matrix provides excellent kinetics and capacity for small biomolecules of both preparative and process scale.

Features Include:

  • A nice balance of pressure-flow characteristics and true
    chromatographic fractionation
  • Successfully applied in simulated moving bed (SMB) applications for a variety of small biomolecules
  • Often compete with bonded silica supports for preparative and
    industrial applications

Methacrylic Type – Diaion® SP2MGS

These feature a small and uniform particle size version of methacrylate types Diaion HP2MG. It gives a higher dynamic capacity than HP2MG and shows strong retention and unique selectivity in normal phase chromatography.

Modified Aromatic Type – Sepabeads® SP207SS

A small size version of modified aromatic type Sepabeads SP207, it’s applied to reversed-phase chromatography.

The brominated polymeric matrix provides:

  • Unique selectivity
  • Full pH operating range
  • Long operating life versus the conventional bonded silica packing materials used in preparative and
    industrial applications
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