NUCLEOSHELL^® – RP 18 PLUS Octadecyl (monomeric) Multi-Endcapping

NUCLEOSHELL RP 18plus is a C18 modified core-shell silica. Its monomeric bonding chemistry enables this HPLC phase to offer hydrophobic characteristics with distinct polar selectivity.

A special derivatization process generates a medium density of bonded silanes with reduced steric selectivity compared to NUCLEOSHELL RP 18.

Low bleeding characteristics makes NUCLEOSHELL RP 18 plus it’s suitable for LC/MS applications, and it provides good stability under highly
aqueous conditions.

Even with long term usage or storage, phase collapse and loss of retention are observed, and original performance can be regained after a short regeneration procedure.

• Based on core-shell particle technology for fast and efficient HPLC
• Hydrophobic C18 phase with distinct polar selectivity, ideal for method development
• Excellent performance under highly aqueous conditions
• Monomeric octadecyl modification
• Multi-endcapped; pore size 90 Å
• Particle size 2.7 µm with carbon content 5.7 %
• Particle size 5 µm with 4.4 % C
• pH stability 2-9; suitable for LC/MS