Cyano HPLC Semi-Prep

Cyano Bonded Phase can also be used in Reversed Phase mode.  However, since the number of carbons between the silica gel surface and the terminal cyano group is small, the retention is not as strong as C18 or C8. That is, Cyano Silica is the least reactive of the silica phases in Reversed Phase mode so the retention times are low, which means a shortening of separation times. 

• Cyclosporins from serum/blood 
• Antidepressants from serum 

• Benzalkonium Chloride from aqueous solution 
• Beta-blockers from serum 
• Carbohydrates from aqueous solution 
• Narcotics from plasma 
• Herbicides from water 

Cyano HPLC Semi-Prep is available in porosities of 100Å, 300Å, and 500Å and particle sizes of 5µm, 10µm, and 15µm. 

Cyano HPLC Semi-Prep is manufactured on Sorbtech’s Premium Rf Spherical Silica Gel which boasts narrow pore and particle distributions, ensuring optimal selectivity, capacity, efficiency, low operating pressure, and shorter processing time. 

Premium Rf Spherical Silica Gel is manufactured to a high chemical purity standard (99.95% SiO2).  Organics and trace metals content are controlled within stringent limits.  Each production batch has undergone extensive quality control testing to ensure reliable lot-to-lot performance.  This rigid control of chemical purity, surface area and pore size, ensure our silica will yield reproducible separation results and allow for direct scale-up without requiring time-consuming method redevelopment. 

Our spherical silicas are mechanically robust and can, therefore, be repacked multiple times in either analytical or preparative scale columns.