Amino HPLC Analytical
The Amine functionalized Silica Gel phases are designed to address the following applications:
- Basic compounds such as alkaloids in Normal Phase mode (using Normal Phase organic solvents)
- Separation of vitamins or sugars in Reversed Phase mode (using water and water miscible solvents)
- Metal scavenger – removal or recovery of acid chlorides, isocyanates, etc.
Precursor for the development of chiral stationary phase packings
The silanol groups on the surface of bare silica gel can act as a Bronsted acid (silicic acid). This means they can adsorb basic compounds by ionic bonding. The modified silica surface, treated with an amino-propyl silane by chemical bonding, eliminates the ionic interactions with basic compounds. Without this treatment, the ionic bonds have strong effects on basic solutes, adsorbing the basic solute to the surface of the silica gel, which causes the solutes to elute from the column with tailing and low yield.
The Amine functionalized Silicas serve multiple functions depending on conditions.
Recommended applications include: As Normal Phase for basic compounds like alkaloids; as a Reversed Phase for vitamins or sugars; metal scavenger removal/recovery for acid chlorides, isocyanates, etc.; dyes, lipids, mycotoxins, pesticides.
For HPLC, UHPLC, SFC, or Capillary LC
Amino HPLC Analytical is available in porosities of 100Å, 150Å, 200Å, and 300Å and particle sizes of 2µm, 3µm, 5µm, and 10µm.
Quality and Diversity
Amino HPLC Analytical is manufactured on Sorbtech’s Premium Pure™ Spherical Silica Gel which boasts very narrow pore and particle distributions, ensuring optimal selectivity, capacity, efficiency, low operating pressure, shorter processing time; and are therefore, the best balance between high performance and value.
Purity
Premium Pure Spherical Silica Gel is manufactured to a very high chemical purity standard (>99.99% SiO2). Organics and trace metals content are controlled within stringent limits. Each production batch has undergone extensive quality control testing to ensure reliable lot-to-lot performance. This rigid control of chemical purity, surface area and pore size, ensure our silica will yield reproducible separation results and allow for direct scale-up without requiring time-consuming method redevelopment.
Robust
Our spherical silicas are mechanically robust and can, therefore, be repacked multiple times in either analytical or preparative scale columns.
